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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9729bd91a290f4573aade2eec2120e46ce9d1ee67e3ee07363a3c62776e1a023' 
  AND token = 'MlVgUH9N29kEq9f8fL+xoDcC9XnqhZ4HCuEfpiOimTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}