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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b77d7e23ad0e20c0d25da32973af5b8096b977fa892d05ffcf52839b8affddd' 
  AND token = 'MQWU3HzdjR7YUMpUCUnE+eP3hiwdQ8LGqJ0NuCguj48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}