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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd580d42587002b770b583cd555bf78b83194cc8125fea632f43149a95b096e34' 
  AND token = 'qlkciv27/Vua/8vwucNnypgEtaTT1xj6u+ZFNCag3Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}