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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449c8cbeb86dcbb52e1325110534a8f7db5c4ad0e565b87b9d12f8dfb94e82be' 
  AND token = 'V/zmciStGVmWDGfDCrwfET6DnmCgZrjUCXUI9GTIDQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}