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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4051a461567e530d9682aa09e5f127d7ec81d40fadaa8b81c96b38346e8af6' 
  AND token = 'pnTrLQFsA+ZI9fS4WLqYDlRm+aNDR2bRmILn65G6LF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}