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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6281c7684472f5d86f0fa6dbade0d20449440fd627e921deb720d10c7c7319' 
  AND token = 'ekt3AHSfNlKXtTgkg+/bHvbZ10KauaT189ULS20pO8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}