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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a9ee5be60f2d12f285a7e68ec74d9bf1b75b4d7f78e045bbdf0f01c5e34706' 
  AND token = 'kosHYRF95VpO1pfCw+AqJ9IQa2G8DM1KO0Fphv7tc8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}