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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3949fd539df4d701b299cfde9729700915cee872ae51cb8cb4874f4bd8e5d6' 
  AND token = 'FsAqZwhdKvOnyy9AW5DRhz5682O+v3lNJ9TPyDoL0EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}