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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4331b01226be9b06e98c08d0a71cedf4636f8b71deae8cdfec70eaf6ce951848' 
  AND token = 'T+p4ZgA7+yDSw+1g/nL4N1ODQidsX5HKRC+Vc0L/0j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}