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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1357a2efa4e10c804a327fc17bdda6b4c0b5d1ea375028dc5b769afc09a9d9e1' 
  AND token = 'U7C6Z9mwGf4+vSXVQ3Ym3kzUu4Hm4pUg7359vsy5PEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}