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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600d2ee8b19d07602fbe7784603cef8126c1b3c61b442ab478a3f7af92ba5c11' 
  AND token = 'PBTSEAMFPGuxFe+eIoLo8kG9e0PeZLRC7oSoYdFUoaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}