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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e27583e3b3d3d4c29611cb7351df59356a3781cf03f89af9ae11d755092db93' 
  AND token = 'x66h38eMbhI1hHLILFONPEZxLSoxqGm1SPUCFdpdaTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}