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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd60f06c6a749bfb5cdf746b0275dc597720bea1baee74a423d5d6b7435d64709' 
  AND token = 'Yt30mt++5Z52pVtjVf1pfrp9eTCzSBKie4FBPGtWjIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}