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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd9d1f077398e491ff173f5e9923e48d9b096e2e0f0afa6742a73d11c1324d7d' 
  AND token = '+LKV+V05zi73X3gMJS5UxmX5zyBMARxAhwssUjxdH1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}