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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e5be5ea1399ec9c16eeb8f62b4e454da5f53e62a2f13d927ac66fdabf605393' 
  AND token = 'iSSj2SiWkWPERt8mKddf6xK6VgGp5tA8GyAoj5Qcmu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}