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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a45a814ea0dc593ee98decdbb8ea97780ad84d569d08040fba7fcbca750a44b' 
  AND token = 'FHoEPK9hfWKTe9lY+kG8oDcro9rDldxWkN/MXTY/9Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}