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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f63cf89bd5e66e636c2f5fa7cb28566a2695412b36614b346b36b707f0de0b5' 
  AND token = 'Zc3hyu16Cv9a6JtOtmYn5HwMvRcVhk3XvzfSAZK0m/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}