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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6767b4f3165ed282152bc3dd4d22ba0b1efc3d951ee62bc3d3253d84b1f5700a' 
  AND token = '8OEm4rLmdwjUxbQVDSDYbRSkU+uNcfOloBV/AsmXt2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}