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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125c6598d2a22e276d8564039dc5edcc390afa3caccc9347273e0f56e691cae8' 
  AND token = 'eSR88UN9km8TdQjhTfr//xIoWSgXeKMIjqK0seAdy6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}