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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '872aa7e1b5b9bb2fcfe33af7563ee72f2cdc1e08d82b7356699b29799fc71509' 
  AND token = 'jMtmLbjhtxvRfrcqTb6NbKR/K5s15EQobnnysvbQ0jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}