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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb72f27d14e89b45e2ba46aa9a793928ce693d0d33338bc1f0d05bab6005c3c8' 
  AND token = 'sFTU9Pk3kj2RYIBvuXvaiY+ih90GtcxXx07QJhT2UzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}