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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c64cf66bbf444c8076652caa034682e24294d2759da4e595018e3ac1ff412a37' 
  AND token = 'GKsYEwGBfq8ke+JD0Wbc2nkEy3CKrXR4DbcBgbsGZaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}