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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf21ff50acf0f51e5136c37fbabf952df2a0d0ba333896ccb9ac6da66add9a96' 
  AND token = 'laDUz/GW66DlU6jQIi+gdUbkDYILG9uQm0aQqsq3FWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}