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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a091277cadb875fdc6b60314ab382c3fd2c2d45bce2f5537e87c6d6db3fa35' 
  AND token = '5W/iOUEOWbYZ6MipSgvxdAEPQdvqyZ2X3ooeLz8GcC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}