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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49689e925c11b6160e794fc605c1c210f417f4e715a035bb224b1cfd0289ae43' 
  AND token = '3rSAI9MaJP471/zRt6k7jelEai2A1wBpHoKBkSy/RM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}