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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f39fd1ca44222ac7d7696fc25476edd0d19d8cd9366d4c442607a17c3f71a59' 
  AND token = 'QpRTfxk3/QPzph0AUiTuzfYxhcldYsXWzlGJfoz9OZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}