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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654d7d09183aab0678fc2db8bd06952b54e9c428d3f9f5284735dc86bac4566b' 
  AND token = '2pfBnOWxuugdQFF2SNx5yqzqz2izGVxsQHYfvODN15U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}