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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd104133ec4f5c10272e4051c14f1e389b3772d08bdedcc4651935ece17e53a37' 
  AND token = 'CXX/StsotcKFIMNQWpnpcAAH25ZD9sdRKDZ6MSzMR4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}