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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ef908740d3638c0e7ed325c83e93d67c7489bd6e963aced4a97c4177827149' 
  AND token = 'Zi3dB8ynjbG5FEL+hOP1xw6BVTH3e1SSKBEW+8hCrqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}