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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af83fd37d3e52f43a4a3296d0a162e545cd40f04ca58a6d302302a5fd671b115' 
  AND token = 'Es2voQkhy2Gl2p3Z1rmtEg9i1xfic+6/0bg5uMg5WN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}