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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe637c4fdf47b50ed684910fb1739267de81428cff209c73ae440daffb85796' 
  AND token = 'O+0OdPS4+Q/rSEU/QpzR85txWlofQ7b4NxRf9wRSikc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}