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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e410a0dc99ff77c52200826223c84572a9a78de69bb3d1aba556478f9acd1a5d' 
  AND token = 'rNYmnjRa1bUhOZHpTSjSd0B29znDpAjLVmpjX+ldQA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}