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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b5c6cda594aa2abd5dcf872e6a4962268cf73c6b6b34b3c108c23819a3ee9b' 
  AND token = 'pKjMoOjqVMr7qgSMT5E3lMPZAVqTXvqLb09lt3Vc2Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}