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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27168159ae03a2ca3148f75c59c132b9c5ef49ad6e6be86ab8456d8e9d68973e' 
  AND token = 'tR5U7Tt/HuxCaPam+jsRVJ3AU6SrCFDaVKgGcfNHLpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}