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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b1c2cf4c3ce6e7d5fc78349d02e6b5eb68a939831db111d072b9a91ca4618a' 
  AND token = 'OLYjw2xuWknyEZCQOZtAZf/ngwnzEONG7nrYJPu0Ukc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}