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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e188bea43fdf5c6b6d7a84b6a8325ffa12c83ddd41b89b011858a4a808682392' 
  AND token = 'CUDj1OsB5iQWtjL4BPqCrUsoZ+PVhT9oTV1Om6Pr+us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}