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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede58148619ef01e424addc141810516e78abf28447a6e140849cfb21d62a27b' 
  AND token = 'DtlOkWa/wX5V0fjLEGGJ5xITfx/OPWuR32NS0i2ntZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}