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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '269b39d3b06b952c312a3b40d1022bbabc8fe2484db700d3f86cc556e4213b64' 
  AND token = 'uYrXseWoDZ7wI+61JK08vq54PQRK2hZmEULU3cfdI3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}