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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5febab11798fa218b0f3159d0c614015350d6abd6a23c3fc857e1e9ca0e78dab' 
  AND token = 'j4OamCr21EKSN3jywUlfMuNWNuUoYnY7zLEfSftfsoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}