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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd89b86945d4fa37994cd66805f2b3c734c31c4fbae9022b1f289ba2fc2b3096d' 
  AND token = '+6DT0HdPS5E5RKUboT61VMiTEmSo6UbgdO9IaSq6AY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}