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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e04779e0803450dc46d86fdfb4e7e6ddeee14d86860703db4b23d5c3437903a' 
  AND token = 'n9Iq3OhPPXAeeflfzJazWIskVPXE+a16BZI50up+tTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}