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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4853079bbccc9971f86c03d7dac3488add57abdd7e9485e0f2683c7516d980' 
  AND token = 'V4jQJZsO6RKs9O0Sc0bQiQRTEPxDWBMFyoeFW6yW0UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}