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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36a419b73d71a9a1f268949c8f087a39f66df700945233006da8461c2de9fc49' 
  AND token = 'S4B9MC0T+HtG2KWc3AEManv4rOO3+4kqcuH9WNX5Q04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}