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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '104f13439aa002bf9443ee122b591d138a61629a859df37b33264ee73b17b0d8' 
  AND token = 'YMLVCNHaf2K1JnWS+/PWjZMAIdMm/TlHUD0c6vKV1dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}