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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ba0efb99cc1e2f86fa8e208133d83e5b02c4576ec726d1749f23c3a0108b3b' 
  AND token = 'eSNBlNjrDYdNsdBgNY+uNPZ63aOG3pL/IGZ2xb0u74c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}