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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e07ffa4b977e0f24960882e8daa0a5705a9a8138a7b8d63322bbe06bcb678209' 
  AND token = 'kxBL6KdXyHG8aQzp6P3JCO3rT37BSD4NRN+A5yUjYlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}