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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '314b5e592d4b936894e522772d60233e7e491c2c361142653f7e4d3d26f0341b' 
  AND token = 'NesYPAbojsh7mW4C5nE1POjjED6l6WSt7XsXkKmaRss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}