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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c0dfb41258995201becde2e8104d3771efe2c6dd9b7a809c8c2b3e00f5f811' 
  AND token = 'F7mIqCzHVHVcehLWdRTUTd5Wq5wvF2plnRiy3jMGi28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}