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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b10eb9eace2fcee92f11b597b58957aaace96941db4ab9dca65fd436917a40' 
  AND token = 'N0Nm4e1r/fYWK3I5Qt5W23kxxmLayhKNY/9DJoiXSEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}