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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d98dcff233b078f58d731f327ba141b8758eee72e08e48c76062a6b46140ba' 
  AND token = 'gj5RKL4XbjFQXO6lRTSGjLooReb9PK64DtfZpH2/uh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}